Notes and Practice Activity on Important Introductory Biology Concepts: Definition of Biology, Scientific Method, and the Characteristics of Life
Notes and Practice Activity on Important Cell Concepts: History Leading up to the Cell Theory, the Cell Theory, Bacteria vs. Virus, Prokaryote vs. Eukaryote, Plant Cells, Animal Cells, Cell Substructures, and the Cell Membrane
Notes and Practice Activity on Important Ecology Concepts: Habitat & Levels of Organization, Symbiosis, Ecological Pyramids, Ecological Succession, Biochemical Cycles, Population, Keystone Species, Eutrophication, Biomagnification, and Global Warming
Notes and Practice Activity on Important Evolution Concepts: Theories of Biological Change, Theories of Geological Change, Charles Darwin's Theories, Natural Selection, and Evidence of Common Ancestry
Notes and Practice Activity on Important Molecular Biology Concepts: Theories of Gregor Mendel, Chromosomes, Monomers, Evidence for DNA, Chagraff's Puzzle, Watson and Crick, Nucleotide, and DNA structure
Notes and Practice Activity on Important Biochemistry Concepts: Water Properties, Acids, Bases, and Macromolecules.
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In this lesson...
- What is Biology?
- Scientific Method
- Steps
- Vocabulary
- Characteristics of Life
What is Biology?
The study of organisms
Scientific Method
● Steps
○ Identify a problem
○ State observations about the problem
○ Form a hypothesis about the problem
○ Design an experiment to test the hypothesis
○ Collect data
○ Form a conclusion
● Vocabulary
○ Observations
■ 5 senses used to gather evidence
○ Hypothesis
○ Experiment
■ Procedure used to test hypothesis
○ Variable
○ Control variables (constants)
■ Factors that are the same for all groups
○ Control group
○ Other Variables
■ Independent Variable
● Factor that is changed and tested
■ Dependent Variable
● The factor that is measured or observed
○ Data
■ Quantitative data
● Results in numbers
■ Qualitative data
● Results in letters
○ Conclusion
■ Inference
● Idea or conclusion that is drawn from evidence and reasoning
■ Theory
● Hypothesis or a group of hypotheses that have been supported by repeated testing
■ Law
● Body of observations
Characteristics of Life
● Cell organization
○ Unicellular
○ Multicellular
● Reproduction
○ Asexual reproduction
○ Sexual reproduction
● Growth and development
○ Ex: Change in height and weight
● Response to the environment
● DNA
○ Your genetic makeup
● Obtains and uses energy
○ Anabolism
■ The process of building up complex substances from simpler substances
● Ex: Building up cells and cellular components
● Photosynthesis
○ Catabolism
● Cellular respiration
○ Metabolism
● Homeostasis
○ Stable state of conditions in the body that are necessary for life
○ Ex:
THESE ARE ALL NECESSARY TO LIVING (BIOTIC) ORGANISMS!!!! IF SOMETHING DOES NOT HAVE ALL OF THESE THEN IT IS NOT LIVING (ABIOTIC)!!!!!!!!
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In this lesson...
- The Cell
- The Events that Led up to the Cell Theory
- Cell Theory
- Bacteria vs. Virus
- Prokaryote vs. Eukaryote
- Animal Cells
- Plant Cells
- Cell Substructures
- Cell Membrane
- Phospholipid Bilayer
- Additional Elements/Characteristics
- Mitosis and Meiosis
The Cell:
● Smallest and most basic unit of life
● The Events that Led up to the Cell Theory:
- 1665: Robert Hooke
- Observed the remains of dead plant cells
- Observed and named cells
- 1675: Anton van Leeuwenhoek
- First to see cells under a microscope
- 1838: Matthias Schleiden
- Concluded that plants were made of cells
- 1839: Theodor Schwann
- Concluded that animals were made of cells
- 1855: Rudolf Virchow
- Said that cells are made of cells
● Cell Theory (From Schleiden, Schwann, and Virchow)
○ All living things are made of cells.
○ Smallest living unit structure and function of all organisms is the cell.
○ All cells arise from the preexisting cells.
■ Discards the idea of Spontaneous Generation (some organisms come from thin air)
Bacteria vs. Virus: Bacteria Virus
-------------------------------------------------------------------------------------------------------------------------
Living Yes No
-------------------------------------------------------------------------------------------------------------------------
Number of Cells 1 None
-------------------------------------------------------------------------------------------------------------------------
Reproduction Yes No
-------------------------------------------------------------------------------------------------------------------------
Size 0.5-5.0 micrometers (length) 5-300 nanometers
Prokaryote vs. Eukaryote: Prokaryote Eukaryote
-------------------------------------------------------------------------------------------------------------------------
Examples Bacteria Cell Plant Cell
-------------------------------------------------------------------------------------------------------------------------
Nucleus No Yes
-------------------------------------------------------------------------------------------------------------------------
Organelles No Yes
-------------------------------------------------------------------------------------------------------------------------
Cell Wall Material Peptidoglycan Cellulose
-------------------------------------------------------------------------------------------------------------------------
Ribosomes Yes Yes
-------------------------------------------------------------------------------------------------------------------------
Cell Organization Unicellular Multicellular
Animal Cells:
● Eukaryotic cell
● Parts of this cell:
○ Cell membrane
Cell Substructures:
● Three substructures:
○ Hypertonic
○ Isotonic
○ Hypotonic
Cell Membrane:
● Made up of a phospholipid bilayer
○ Several names for it:
● Phospholipid Bilayer
○ Semi-permeable: some things can move in and out of the cell membrane freely (oxygen or carbon dioxide), while others cannot (polar and large molecules)
○ Maintains homeostasis
○ Made up of two parts: Phospholipids and proteins
● Phospholipid
○ Has a phosphate head and two tails (fatty acid chains).
Additional Elements/Characteristics:
● Passive Transport:
○ Movement of molecules from a high concentration to a low concentration
○ Requires no energy (ATP)
○ Examples:
● Active Transport:
○ Moving low to high concentration
○ Requires energy (ATP)
○ Against concentration gradient
● Simple Diffusion
○ Going with concentration gradient
○ No energy (ATP) needed
○ No protein channel required
○ Example:
■ O2+CO2
● Osmosis
○ Movement of water from a high concentration to a low concentration
○ Energy (ATP) not required
○ Passive transport
● Facilitated Transport
○ Passive from high to low concentration
○ No energy (ATP) needed
○ Needs protein channel
● Endocytosis
○ Movement of large molecules into a cell
○ Requires energy (ATP)
○ Moves from low to high
● Exocytosis
○ Active transport
○ Requires energy (ATP)
○ Movement of large molecules out of the cell
○ Against the concentration gradient (low to high)
Mitosis:
Prophase: Chromatin begins condensing into chromosomes. The chromatids are joined together by a centromere.
Metaphase: the chromosomes line up in the middle of the cell.
Anaphase: chromosomes break at the centromere and sister chromatids move to opposite ends of the cell.
Telophase: A nuclear membrane forms and chromosomes begin to unwind and separate. Cytokinesis: The cytoplasm divides and forms two new cells.
Meiosis is the same thing, but it just happens one more time, resulting in four daughter cells instead of two.
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**To view images, please use the PDF version of the notes**
In this lesson...
- Habitat & Levels of Organization
- Symbiosis
- Ecological Pyramid
- Ecological Succession
- Biochemical Cycle
- Population
- Keystone Species
- Eutrophication
- Biomagnification
- Global warming
Habitat & Levels of Organization:
● Ecology:
○ The study of interactions that take place between organisms and their environment
● Habitat:
○ Place a plant or animal lives
● Niche:
○ An organism’s total way of life
● Abiotic factors:
○ The nonliving parts of an organism’s environment
○ Include air currents, temperature, moisture, light, and soil
○ Affect on an organism’s life
● Biotic factors:
○ All the living organisms that inhabit an environment
○ Organisms depend on others directly or indirectly for food, shelter, reproduction, or protection
● Simple levels:
○ Atom
○ Molecule
○ Organelle
○ Cell
○ Tissue
○ Organ
○ System
● Levels of organization:
○ Organism/Species
■ An individual living thing that is made of cells, uses energy, reproduces, responds, grows, and develops
○ Population
■ A group of organisms, all of the same species, which interbreed and live in the same place at the same time
○ Community
■ All the populations of different species that live in the same place at the same time
○ Ecosystem
■ Populations of plants and animals that interact with each other in a given area with the abiotic components of that area (terrestrial or aquatic)
○ Biosphere
■ The portion of the Earth that supports life
● Organism groups:
○ Autotrophs
○ Chemotrophs
○ Heterotrophs
■ Organisms that do not make their own food
● Also called consumers
● Scavengers, herbivores, carnivores, omnivores, and decomposers are all heterotrophs
● Examples:
○ Rabbits
○ Deer
○ Mushrooms
Symbiosis:
● The relationship between 2 organisms of different species that benefit one or both organisms
● Mutualism
○ A symbiotic relationship that benefits both organisms involved
● Commensalism
○ A symbiotic relationship that benefits one organism and the other is not helped or harmed
● Parasitism
○ A symbiotic relationship that benefits one organism and the other is harmed
Ecological Pyramids:
● Models that show how energy flows through ecosystems
○ Represent trophic levels Pyramid of Energy:
● 10% of energy is passed from one trophic level to the next
● Most of the energy is lost as heat
● Each level represents the amount of energy that is available to that trophic level
● As you move up the pyramid, the energy decreases
Pyramid of Biomass:
● Biomass
○ The total mass of living matter at each trophic level
● As you move up the pyramid, the biomass decreases
● Biomass is measured in kilograms
Pyramid of Numbers:
● Represents the number of organisms present at each trophic level
● As you move up the pyramid, the number of organisms decreases
Ecological Succession:
● Natural or gradual changes in the types of species that live in an area
● Primary succession (volcanoes or glaciers):
○ Lichens that do not need soil to survive grow on rocks
○ Mosses grow to hold newly made soil
○ Mosses and lichens are known as pioneer species
● Secondary succession:
○ Begins in a place that already has soil and was the home of living organisms
○ Occurs faster and has different pioneer species than primary succession
○ Example:
■ After forest fires
■ Manmade
● Climax community
○ Stable group of plants and animals that is the end result of the succession process
Biochemical Cycle:
● Natural cycles by which a nutrient moves through the environment
● Water cycle (hydrological cycle)
○ Water is needed for all biochemical reactions in the body
○ Transpiration
■ The process by which water is carried through tubes (xylem) in the plants from the roots to small pores (stoma) on the underside of leaves, where it evaporates
● Carbon cycle
○ Organic molecules contain carbon
○ There are four organic molecules (macromolecules):
○ Two processes that cycle carbon:
■ Photosynthesis by plants, algae, and cyanobacteria
● Removes carbon dioxide from air and water and produces oxygen and carbohydrates
■ Cellular respiration
● Returns carbon to the air and oceans as carbon dioxide
● The process of making energy from glucose (sugar)
● Nitrogen cycle
○ Nitrogen is found in proteins, DNA, and RNA in the human body
○ The Earth’s atmosphere contains 78% nitrogen
○ Nitrogen fixation:
■ Lightning or nitrogen fixing bacteria combine and fix nitrogen with hydrogen to form ammonium which can be used by plants
Population:
● A group of organisms of the same species living in a given area
● Exponential growth (makes a J shaped curve)
● Logistic growth (makes an S shaped curve)
● Carrying capacity:
○ The maximum population size that can be supported by available resources
● Density dependent factors:
○ Biotic factors in the environment that have an increasing effect as population size increases
○ Examples:
■ Disease
■ Competition
■ Parasites
● Density independent factors:
○ Abiotic factors in the environment that affect populations regardless of density
○ Examples:
■ Temperature
■ Drought
■ Storms
Keystone Species:
● A plant or animal that plays a unique and crucial role in the way an ecosystem functions
● Without keystone species, the ecosystem would be dramatically different, or cease to exist all together
● Examples:
○ African elephants: help maintain the savannah ecosystem as a grassland instead of a woodland or forest
○ Hummingbirds: Engage in beneficial interactions and pollinate
Eutrophication:
● When lakes, streams, and estuaries are overfertilized causing plants and algae to bloom and eventually die, causing the ecosystem to crash due to lack of oxygen
● Six stages of the eutrophication process:
○ Addition of nitrates
○ Growth of plants (algae)
○ Death of plants
○ Growth of bacteria
○ Lack of oxygen
○ Suffocation
● Biochemical oxygen demand (BOD)
○ The rate of oxygen used by the organism in the ecosystem
○ Used as an indicator for eutrophication
Biomagnification:
● Also known as “bioamplification,” the process by which substances become more concentrated in the bodies of consumers as one moves up the food chain (trophic levels)
● Bioaccumulation
○ The process by which substances not readily broken down or excreted can build up and be stored in living tissue, usually fatty tissue.
● DDT
○ A pesticide that was widely used until being banned in the U.S. in 1972
○ Accumulated in living tissue (fatty tissue)
○ The high concentration of DDT caused failure of eggs and thinning of shells in birds
● Other biomagnification/bioaccumulation chemicals:
○ Mercury
○ PCBs
Global warming:
● Greenhouse gases
○ Gas that is relatively transparent to solar radiation but absorbs and emits in the infrared which is a type of radiation the earth emits
○ Examples:
○ Greenhouse gases make the earth warmer by slowing the loss of infrared radiation
○ Global warming molecules are:
■ Carbon dioxide
■ Nitrous oxide
■ Methane
■ PHS
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In this lesson...
- Early ideas about evolution
- Theories of biological change
- Theories of geological change
- Charles Darwin - Theories
- Natural Selection
- Evidence of Common Ancestry
- Analogous sources
Early ideas about evolution:
● Theories of biological change
○ Linnaeus
○ Buffon
○ Darwin
○ Lamarck
■ Environmental change leads to use or disuse of a structure
● Theories of geological change
○ Catastrophism
○ Gradualism
○ Uniformitarianism
Charles Darwin:
● Observed variation among island species
○ Species: Organisms so similar they can reproduce and produce fertile offspring
○ Mutations caused differences in physical traits in individuals and populations
○ Variation is a difference in a physical trait
■ Example: Galapagos tortoises have long necks and legs in contrast to regular tortoises
● Realized species could adapt to their environment
○ Species are able to adapt to their environment
○ Adaptation is a feature that allows an organism to better survive in its environment
■ Can lead to genetic change in a population
● Observed fossil and geologic evidence of an ancient earth
○ Fossils preserve traces of an organism from the past
○ Fossils are links between stages of evolution
● Natural Selection
○ A mechanism by which individuals that have inherited beneficial adaptations produce more offspring on average than other individuals
○ Four main principles of natural selection:
● Key insights that led to his theory
○ Artificial selection
■ How humans use plant and animal breeds to develop phenotypic traits
○ Heritability
■ The ability of a trait to be passed down
○ Struggle for survival
■ Due to overpopulation and limited resources
Evidence of Common Ancestry:
● Fossils
○ Provides evidence of evolution
■ In older layers are more primitive than those in upper layers
● Geography
○ Provides evidence of evolution
● Embryology
○ Provides evidence of evolution
● Anatomy
○ Provides evidence of evolution
■ Homologous structures
● Similar in structure but different in function
■ Vestigial structures
● Remnants of organs or structures that had a function in an early ancestor
● Analogous Structures
○ Not evidence of a recent common ancestor
○ Have similar function to homologous structures
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In this lesson...
- Gregor Mendel
- Chromosome
- Monomers
- Evidence for DNA
- Chagraff’s Puzzle
- Watson and Crick
- Nucleotide
- DNA structure
Gregor Mendel:
● Mendel was the father of genetics
● He studied heredity in peas because:
○ They grew fast
○ Had many varieties
○ They were small
● Heredity is how genetic information is transferred to offspring
Chromosome:
● Located in the nucleus
● DNA is wrapped around the protein histones
Monomers:
● A building block
● Carbohydrate’s monomers is monosaccharide
● Building block of nucleic acid is nucleotide
● Protein’s monomer is amino acid
● Two types of nucleic acid:
○ DNA ○ RNA
Evidence for DNA:
● A vaccine is made from dead or weakened bacteria
● You are given the vaccine and you are ready for the live version
● Virulent (pathogen): a substance that causes disease or death
● Bacteria is the only organism that can perform transformation
● Genetic information is transferred through DNA
● Bacteriophage is a virus that infects bacteria
Chagraff’s Puzzle:
● Complementary pairs
○ A - T, C - G, T - A, G - C, T - A, C - G
● Pyrimidines = Cytosine and Thymine
● Purine = Adenine and Guanine
Watson and Crick:
● Two men that built the first model of DNA
● They won the Nobel Prize
● Some scientists say that Rosalind Franklin, who was the first person to take a picture of DNA, using an X-ray, should have won the Nobel Prize
Nucleotide:
● Made up of three things:
○ A nitrogenous base (a nucleo base)
○ A five carbon sugar (ribose or deoxyribose)
○ A phosphate group (1-3 phosphates)
● Four nitrogenous bases:
○ Adenine (A)
○ Cytosine (C)
○ Guanine (G)
○ Thymine (T)
DNA structure:
● The backbone of DNA is made up of:
○ Phosphate groups
○ Sugar groups
● The rings consist of one oxygen and four carbons
○ The fifth carbon atom is attracted to the fourth carbon of the ring
● The bases are two of the four nitrogenous bases:
○ Adenine (A)
○ Cytosine (C)
○ Guanine (G)
○ Thymine (T)
Here it is! You have the option to download these files or read the notes directly on this page!
In this lesson...
- Water Properties
- Acids and Bases
- Macromolecules
Water
Properties:
● Polar
○ Water has unequal charged ends
● Cohesion
○ Attraction between properties of the same substance
○ One water molecule bonding to another water molecule
○ Example: Water touching water
● Adhesion
○ Attraction between two different substances
○ Examples:
■ Capillary action
■ Transpiration
● Surface Tension
○ A film on water caused by cohesion
○ Example:
■ Produces a surface that allows insects to walk on the surface of water
● Capillary Action
○ Water molecules will “tow” each other along similarly to a thin glass tube
○ Example:
■ Transpiration
● Transpiration
○ Process in which plants and trees remove water from the soil, and paper towels soak up water
● Solute
○ Substance being dissolved
○ Example:
■ Salt
● Solvent
○ Substance into which solute dissolves
○ Example: water
● Buffer
○ Made of a weak acid or base that absorbs additional H+ or OH- ions so that the solution will maintain a stable pH
○ Example:
■ Baking soda, Tums
● Indicator
○ A substance that changes color in the presence of an acid or base ○ Example:
■ Cabbage juice
● Organic
○ Contains carbon
● Monomer
○ Building blocks of macromolecules
● Polymer
○ Macromolecules
● Hydrolysis
○ Separates monomers by “adding water”
● Dehydration Synthesis
○ Forms polymers by combining monomers by “removing water”
Acids and Bases:
Acids:
- Taste: sour
- Examples: Hydrochloric Acid, Acetic Acid
- Reaction w/ metals Kind of ion: React
- pH numbers: H+ 0-6.9
Bases:
- Taste: bitter
- Examples: Acetone, Ammonia
- Reaction w/ metals Kind of ion: Don’t React
- pH numbers: OH− 7.1-14
Neutral Substances:
- Taste: --
- Examples: water
- Reaction w/ metals Kind of ion: --
- pH numbers: 7.
Macromolecules:
● Organic: contains carbon
● Carbon
○ Can form covalent bonds as many as 4 other atoms (elements)
● Macromolecules (Polymers)
○ Large organic molecules
● Monomer
○ Building blocks of macromolecules
○ Each polymer has a different monomer
Monomer - Polymer
Monosaccharides - Carbohydrates
Fatty Acids - Lipids
Amino Acids - Proteins
Nucleotide - Nucleic Acids
● Dehydration Synthesis (condensation reaction):
○ Forms polymers by combining monomers by “removing water”
● Hydrolysis
○ Separates monomers by “adding water”
● Carbohydrate
Monomer : Monosaccharide
Function : Short term energy
Elements : Carbon, hydrogen, oxygen
Shape : Ring
● Monosaccharide
○ One sugar unit
○ Examples:
● Disaccharide
○ 2 sugar units
○ Examples
● Polysaccharide
○ Many sugar units
● Types of Carbohydrates:
Starch : How plants store glucose
Glycogen : How animals store glucose
Cellulose : Makes up plant cell wall (fiber)
● Lipids
Monomer : Fatty Acids (Triglyceride)
Function : Long term energy, cell membrane
Elements : Carbon, hydrogen, oxygen
Shape : E-shape
● Lipid Examples
○ Fats
○ Phospholipids
○ Oils
○ Steroid hormones
● Saturated Fats: no double bonds (Bad)
● Unsaturated Fats: no double bonds (Good)
● Protein
Monomer : Amino Acids (20 different kinds)
Function : Body Structure (muscles, organs), enzymes
Elements : Carbon, hydrogen, oxygen, nitrogen
Shape : No set shape; Shape determines function
● Enzymes
○ Proteins
○ Speed up chemical reactions and require little energy (ATP)
○ Put things together and take them apart
● Nucleic Acids
Monomer : Nucleotide
Function : Contain genetic information
Elements : Carbon, hydrogen, oxygen, nitrogen, phosphate
Shape : Helix
● Nucleotide
○ Phosphate group
○ Sugar (5 carbon)
○ Nitrogenous Base
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